Description

2,2,2-Trifluoro-1-(Pyridin-3-Yl)Ethanamine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoroethylamine moiety attached to a pyridine ring makes it an essential intermediate for creating compounds with enhanced metabolic stability and bioavailability. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Research: Used in the synthesis of novel herbicides and pesticides, where the fluorine atoms contribute to lipophilicity and membrane permeability.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Building block for specialty polymers and advanced materials requiring fluorine incorporation for specific thermal or chemical resistance properties.
• Fluorine Chemistry Library: A valuable compound for constructing diverse screening libraries in medicinal and agrochemical discovery programs.

Basic Information

Product Name	2,2,2-Trifluoro-1-(Pyridin-3-Yl)Ethanamine
CAS No.	912761-24-1
Molecular Formula	C7H7F3N2
Molecular Weight	176.14 g/mol
Synonyms	3-(2,2,2-Trifluoroethylamino)pyridine; 1-(3-Pyridinyl)-2,2,2-trifluoroethanamine; 2,2,2-Trifluoro-1-(3-pyridyl)ethylamine; α-(Trifluoromethyl)-3-pyridinemethanamine; 3-(Aminomethyl)pyridine, α,α,α-trifluoro-; 3-Pyridinemethanamine, α,α,α-trifluoro-; 2,2,2-Trifluoro-1-(pyridin-3-yl)ethan-1-amine
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(Pyridin-3-Yl)Ethanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.