Description

3-(5-Bromo-2-Methoxy-Pyridin-3-Yl)-Acrylic Acid Ethyl Ester is a high-value pyridine-based acrylate ester, serving as a critical synthetic intermediate in advanced organic chemistry. This compound is prized for its versatile reactivity, particularly in cross-coupling reactions and as a Michael acceptor, enabling the construction of complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and functional materials.
• Cross-Coupling Reactions: Utilized in Suzuki, Heck, and other palladium-catalyzed coupling reactions to introduce the functionalized pyridine moiety.
• Chemical Biology: Employed in the design and synthesis of molecular probes and bio-conjugates.
• Academic & Contract Research: A valuable reagent for synthetic methodology development and library synthesis in research laboratories.

Basic Information

Product Name	3-(5-Bromo-2-Methoxy-Pyridin-3-Yl)-Acrylic Acid Ethyl Ester
CAS No.	912760-94-2
Molecular Formula	C11H12BrNO3
Molecular Weight	286.12 g/mol
Synonyms	Ethyl 3-(5-bromo-2-methoxypyridin-3-yl)acrylate; Ethyl (E)-3-(5-Bromo-2-methoxypyridin-3-yl)acrylate; 3-(5-Bromo-2-methoxy-3-pyridinyl)-2-propenoic acid ethyl ester; 5-Bromo-2-methoxy-3-pyridineacrylic acid ethyl ester; (E)-Ethyl 3-(5-bromo-2-methoxypyridin-3-yl)acrylate; 912760-94-2; Acrylic acid, 3-(5-bromo-2-methoxy-3-pyridinyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our 3-(5-Bromo-2-Methoxy-Pyridin-3-Yl)-Acrylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support custom synthesis and can tailor purity grades to meet specific project requirements, from research to GMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.