Description

3-(2-Amino-5-Bromo-Pyridin-3-Yl)-Acrylic Acid is a high-value brominated pyridine derivative featuring both an amino and an acrylic acid functional group, making it a versatile and reactive building block for complex synthesis. This compound is critical for research and development in advanced pharmaceutical chemistry, where it serves as a key precursor for active pharmaceutical ingredients (APIs) and other biologically active molecules. It is primarily sought after by fine chemical manufacturers, pharmaceutical R&D laboratories, and agrochemical companies engaged in the development of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides with specific modes of action.
• Ligand and Catalyst Development: Serves as a building block for creating complex ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers and functional materials with tailored electronic or photonic properties.
• Bioconjugation Chemistry: The acrylic acid moiety allows for potential use in linking molecules to biological entities like proteins or peptides.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemists exploring new reaction pathways and heterocyclic chemistry.

Basic Information

Product Name	3-(2-Amino-5-Bromo-Pyridin-3-Yl)-Acrylic Acid
CAS No.	912760-82-8
Molecular Formula	C8H7BrN2O2
Molecular Weight	243.06 g/mol
Synonyms	3-(2-Amino-5-bromopyridin-3-yl)prop-2-enoic acid; 2-Propenoic acid, 3-(2-amino-5-bromo-3-pyridinyl)-; 5-Bromo-3-(2-carboxyvinyl)-2-aminopyridine; 3-(2-Amino-5-bromo-3-pyridyl)acrylic acid; 2-Amino-5-bromo-3-pyridineacrylic acid; 3-(2-Amino-5-bromopyridin-3-yl)acrylic acid; (E)-3-(2-Amino-5-bromopyridin-3-yl)acrylic acid (potential isomer); 912760-82-8
EINECS	Contact for details

Quality Control

Our 3-(2-Amino-5-Bromo-Pyridin-3-Yl)-Acrylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We can support development projects with custom specifications and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.