Description

3-(2-Amino-5-Bromo-Pyridin-3-Yl)-Acrylic Acid Methyl Ester is a high-value pyridine derivative and an important pharmaceutical intermediate. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories, agrochemical manufacturers, and fine chemical producers engaged in the development of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its bioactive pyridine core.
• Material Science: Serves as a precursor for functionalized polymers and advanced organic materials.
• Academic & Contract Research: Essential reagent for organic synthesis and methodology development in university and CRO laboratories.
• Chemical Library Synthesis: Used in combinatorial chemistry and high-throughput screening for drug discovery programs.

Basic Information

Product Name	3-(2-Amino-5-Bromo-Pyridin-3-Yl)-Acrylic Acid Methyl Ester
CAS No.	912760-74-8
Molecular Formula	C9H9BrN2O2
Molecular Weight	257.09 g/mol
Synonyms	Methyl 3-(2-amino-5-bromopyridin-3-yl)acrylate; Methyl (2E)-3-(2-amino-5-bromo-3-pyridinyl)-2-propenoate; 3-(2-Amino-5-bromo-3-pyridinyl)acrylic acid methyl ester; 2-Propenoic acid, 3-(2-amino-5-bromo-3-pyridinyl)-, methyl ester, (2E)-; 912760-74-8; Methyl 3-(2-amino-5-bromopyridin-3-yl)prop-2-enoate
EINECS	Contact for details

Quality Control

Our 3-(2-Amino-5-Bromo-Pyridin-3-Yl)-Acrylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.