Description

2-(Tetrahydropyran-4-Yloxy)Pyridin-5-Yl Isocyanate is a specialized heterocyclic building block featuring both a pyridine and a tetrahydropyranyl ether moiety, designed for advanced synthetic applications. This compound is valued for its reactivity as an isocyanate, enabling the efficient introduction of the 2-(tetrahydropyran-4-yloxy)pyridin-5-yl carbamoyl group into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates. The CAS number for this compound is 912569-54-1.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery and development programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where its unique structure can contribute to biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers, coatings, and advanced materials with tailored properties.
• Chemical Biology & Proteomics: Employed as a labeling reagent or probe precursor due to the reactive isocyanate group's ability to modify amines and hydroxyls in biomolecules.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex, client-specific molecules.

Basic Information

Item	Details
Product Name	2-(Tetrahydropyran-4-Yloxy)Pyridin-5-Yl Isocyanate
CAS No.	912569-54-1
Molecular Formula	C11H12N2O3
Molecular Weight	220.23 g/mol
Synonyms	5-Isocyanato-2-(tetrahydro-2H-pyran-4-yloxy)pyridine; 2-(Oxan-4-yloxy)pyridin-5-yl isocyanate; 2-(Tetrahydropyran-4-yloxy)-5-pyridinyl isocyanate; 5-Pyridinyl isocyanate, 2-(tetrahydro-2H-pyran-4-yloxy)-; THP-O-Pyridine-5-isocyanate; 912569-54-1; (5-Isocyanatopyridin-2-yl) tetrahydropyran-4-yl ether
EINECS	Contact for details

Quality Control

Our 2-(Tetrahydropyran-4-Yloxy)Pyridin-5-Yl Isocyanate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.