Description

Ethyl 1-[4-(Aminomethyl)Pyridin-2-Yl]Piperidine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a distinct piperidine-pyridine hybrid structure. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of complex drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: A key building block in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) with piperidine-based pharmacophores.
• Bioconjugation & Probe Synthesis: The aminomethyl group enables its use in creating labeled compounds or conjugates for biochemical and diagnostic applications.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	Ethyl 1-[4-(Aminomethyl)Pyridin-2-Yl]Piperidine-4-Carboxylate
CAS No.	912569-46-1
Molecular Formula	C14H21N3O2
Molecular Weight	263.34 g/mol
Synonyms	Ethyl 1-[4-(aminomethyl)-2-pyridyl]piperidine-4-carboxylate; 1-[4-(Aminomethyl)pyridin-2-yl]piperidine-4-carboxylic acid ethyl ester; 4-Carbethoxy-1-(4-aminomethyl-2-pyridyl)piperidine; 912569-46-1; UNII-9VU9B5R8QN; 9VU9B5R8QN; Ethyl 1-(4-(aminomethyl)pyridin-2-yl)piperidine-4-carboxylate; 1-(4-(Aminomethyl)pyridin-2-yl)piperidine-4-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 1-[4-(Aminomethyl)Pyridin-2-Yl]Piperidine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.