Description

Methyl 3-(tert-Butoxycarbonylamino)Picolinate is a high-purity, protected amino acid derivative and a key synthetic intermediate in modern organic chemistry. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing picolinamide or nicotinamide cores.
• Peptidomimetic Synthesis: Used in the construction of peptide analogs and peptidomimetics, where the tert-butoxycarbonyl (Boc) group provides orthogonal protection for the amine functionality.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 3-(tert-Butoxycarbonylamino)Picolinate
CAS No.	912369-42-7
Molecular Formula	C12H16N2O4
Molecular Weight	252.27 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]-2-pyridinecarboxylic acid methyl ester; Methyl 3-[(tert-butoxycarbonyl)amino]picolinate; Methyl 3-(Boc-amino)picolinate; 3-(Boc-amino)picolinic acid methyl ester; 2-Pyridinecarboxylic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester; Boc-3-Amino-picolinic acid methyl ester; 3-(tert-Butoxycarbonylamino)picolinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(tert-Butoxycarbonylamino)Picolinate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.