Description

5,6,7,8-Tetrahydro-1,6-Naphthyridin-2-Amine is a versatile and high-value nitrogen-containing heterocyclic compound, serving as a critical building block in advanced organic synthesis. Its fused bicyclic structure makes it a privileged scaffold for medicinal chemistry, particularly in the development of novel pharmaceutical agents. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the design of new drug candidates.
• Agrochemical Synthesis: Employed in the development of novel herbicides, fungicides, and insecticides due to its bioactive heterocyclic framework.
• Ligand and Catalyst Development: Serves as a building block for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	5,6,7,8-Tetrahydro-1,6-Naphthyridin-2-Amine
CAS No.	912366-00-8
Molecular Formula	C8H11N3
Molecular Weight	149.19 g/mol
Synonyms	2-Amino-5,6,7,8-tetrahydro-1,6-naphthyridine; 1,6-Naphthyridine, 5,6,7,8-tetrahydro-2-amino-; 5,6,7,8-Tetrahydro[1,6]naphthyridin-2-ylamine; 2-Amino-5,6,7,8-tetrahydro-1,6-naphthyridine; THN-2-Amine
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-1,6-Naphthyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.