Description

3A,6,7,7A-Tetrahydro-4H-Isoxazolo[4,5-C]Pyridine-3,5-Dicarboxylic Acid 5-tert-Butyl Ester 3-Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is primarily needed by pharmaceutical R&D laboratories, process development chemists, and manufacturers specializing in complex, multi-step organic synthesis.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of new drug candidates, especially those targeting neurological pathways.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in academic and industrial labs.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for potential APIs under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Utilized to create specialized molecular tools for studying biological systems and enzyme functions.
• Custom Synthesis Projects: A valuable starting material for contract research and manufacturing organizations (CROs/CMOs) working on proprietary client molecules.

Basic Information

Product Name	3A,6,7,7A-Tetrahydro-4H-Isoxazolo[4,5-C]Pyridine-3,5-Dicarboxylic Acid 5-tert-Butyl Ester 3-Ethyl Ester
CAS No.	912265-92-0
Molecular Formula	C15H22N2O5
Molecular Weight	310.35 g/mol
Synonyms	5-tert-Butyl 3-ethyl 3a,6,7,7a-tetrahydro-4H-isoxazolo[4,5-c]pyridine-3,5-dicarboxylate; 3a,6,7,7a-Tetrahydro-4H-isoxazolo[4,5-c]pyridine-3,5-dicarboxylic acid, 5-(1,1-dimethylethyl) 3-ethyl ester; Ethyl 5-(tert-butoxycarbonyl)-3a,6,7,7a-tetrahydro-4H-isoxazolo[4,5-c]pyridine-3-carboxylate; Isoxazolopyridine diester intermediate; BOC-protected isoxazolopyridine derivative.
EINECS	Contact for details

Quality Control

Our 3A,6,7,7A-Tetrahydro-4H-Isoxazolo[4,5-C]Pyridine-3,5-Dicarboxylic Acid 5-tert-Butyl Ester 3-Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.