Description

4-Amino-5-Nitronicotinamide is a high-purity, specialized chemical intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex heterocyclic molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active compounds.

Application

• As a crucial synthetic intermediate in the research and development of new pharmaceutical actives, particularly kinase inhibitors and other targeted therapies.
• For the synthesis of complex nicotinamide and pyridine derivatives with potential biological activity in medicinal chemistry programs.
• In agrochemical research for the development of new herbicides or plant growth regulators utilizing its unique nitronicotinamide scaffold.
• As a versatile building block in academic and industrial laboratories for exploring novel heterocyclic chemistry and material science applications.
• Potential use in the synthesis of ligands for catalysis or functional materials, given its multifunctional amino and nitro groups.

Basic Information

Product Name	4-Amino-5-Nitronicotinamide
CAS No.	911461-18-2
Molecular Formula	C6H6N4O3
Molecular Weight	182.14 g/mol
Synonyms	5-Nitro-4-aminonicotinamide; 4-Amino-5-nitro-3-pyridinecarboxamide; 3-Pyridinecarboxamide, 4-amino-5-nitro-; 4-Amino-5-nitropyridine-3-carboxamide; 5-Nitro-4-aminopyridine-3-carboxylic acid amide; Nicotinamide, 4-amino-5-nitro-; 911461-18-2 (CAS)
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Nitronicotinamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container has been opened. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.