Description

4-Hydroxy-5-Nitropyridine-3-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a carboxylic acid and a nitro-substituted pyridine core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis or metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of specialty dyes, pigments, or advanced materials.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for producing custom compounds in research laboratories.

Basic Information

Product Name	4-Hydroxy-5-Nitropyridine-3-Carboxylic Acid
CAS No.	911461-03-5
Molecular Formula	C6H4N2O5
Molecular Weight	184.11 g/mol
Synonyms	5-Nitro-4-hydroxynicotinic acid; 3-Pyridinecarboxylic acid, 4-hydroxy-5-nitro-; 4-Hydroxy-5-nitro-3-pyridinecarboxylic acid; 5-Nitro-4-hydroxypyridine-3-carboxylic acid; 4-Hydroxy-5-nitronicotinic acid; 911461-03-5; 4-Hydroxy-5-nitro-pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-5-Nitropyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.