Description

2-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol is a versatile and high-value heterocyclic building block of significant interest in advanced organic synthesis. Its unique fused bicyclic structure, featuring both a chlorinated pyridine and a functionalized cyclopentanol ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in the design and production of advanced herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers due to its electron-deficient pyridine core.
• Chemical Biology Probes: Used as a scaffold for developing molecular probes and tools to study biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol
CAS No.	911405-91-9
Molecular Formula	C8H8ClNO
Molecular Weight	169.61 g/mol
Synonyms	2-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol; 7-Hydroxy-2-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine; 2-Chloro-5H-cyclopenta[b]pyridin-7-ol; 911405-91-9; 2-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol (9CI); 2-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol, AldrichCPR; 2-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol (AC1L1VYV)
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the stringent requirements of research and pre-clinical development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.