Description

2-Chloro-6,7-Dihydro-5H-Cyclopenta[B]Pyridine1-Oxide is a high-purity, advanced pharmaceutical intermediate characterized by its fused cyclopentapyridine core and N-oxide functionality. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule therapeutics, particularly within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Used in the construction of heterocyclic cores for potential kinase inhibitors targeting various disease pathways.
• Chemical Synthesis: Employed in organic synthesis for the introduction of the chlorinated cyclopentapyridine moiety into more complex molecular architectures.
• Agrochemical Research: May find application as an intermediate in the development of novel crop protection agents.

Basic Information

Product Name	2-Chloro-6,7-Dihydro-5H-Cyclopenta[B]Pyridine1-Oxide
CAS No.	911405-87-3
Molecular Formula	C8H8ClNO
Molecular Weight	169.61 g/mol
Synonyms	2-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 1-oxide; 2-Chloro-5H-cyclopenta[b]pyridine 1-oxide; 2-Chlorocyclopentapyridine N-oxide; 911405-87-3; 2-Chloro-6,7-dihydrocyclopenta[b]pyridine N-oxide; 2-Chloro-5H-1-cyclopenta[b]pyridinone oxide?; 2-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine N-oxide
EINECS	Contact for details

Quality Control

Our 2-Chloro-6,7-Dihydro-5H-Cyclopenta[B]Pyridine1-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.