Description

2-Amino-3-Bromo-5-(4-Trifluoromethylphenyl)Pyridine is a high-value, multi-functional heterocyclic building block. This compound is critical for research and development in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging the biological activity of the pyridine and trifluoromethylphenyl motifs.
• Material Science: Acts as a monomer or functionalizing agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Employed as a molecular probe or scaffold in drug discovery for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Catalyst Ligand Synthesis: The amino and bromo groups provide handles for constructing sophisticated ligands used in asymmetric catalysis and cross-coupling reactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Product Name	2-Amino-3-Bromo-5-(4-Trifluoromethylphenyl)Pyridine
CAS No.	911113-30-9
Molecular Formula	C12H8BrF3N2
Molecular Weight	317.11 g/mol
Synonyms	2-Amino-3-bromo-5-[4-(trifluoromethyl)phenyl]pyridine; 3-Bromo-5-(4-trifluoromethylphenyl)pyridin-2-amine; 5-(4-(Trifluoromethyl)phenyl)-3-bromopyridin-2-amine; 2-Pyridinamine, 3-bromo-5-[4-(trifluoromethyl)phenyl]-; 3-Bromo-5-(α,α,α-trifluoro-p-tolyl)-2-pyridinamine; 911113-30-9; CAS 911113-30-9
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3-Bromo-5-(4-Trifluoromethylphenyl)Pyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC, Area %)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.