Description

5-Iodo-3-(trifluoromethyl)-2-pyridinamine is a high-purity, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which combines an iodine substituent with a trifluoromethyl group to enable precise structural modifications and introduce desirable physicochemical properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for targeted therapies and enzyme inhibitors.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the halogenated pyridine core is essential for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers and liquid crystals with specific electronic or optical properties.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination.
• Chemical Biology: Employed as a probe or tag in bioconjugation chemistry due to its reactive halogen site.
• Organic Light-Emitting Diodes (OLEDs): Investigated as an electron-transport or host material component in electronic device fabrication.

Basic Information

Product Name	5-Iodo-3-(trifluoromethyl)-2-pyridinamine
CAS No.	911112-05-5
Molecular Formula	C6H4F3IN2
Molecular Weight	288.01 g/mol
Synonyms	2-Amino-5-iodo-3-(trifluoromethyl)pyridine; 3-(Trifluoromethyl)-5-iodopyridin-2-amine; 5-Iodo-3-trifluoromethyl-2-pyridylamine; 2-Pyridinamine, 5-iodo-3-(trifluoromethyl)-; 5-Iodo-3-(trifluoromethyl)pyridin-2-amine
EINECS	Contact for details

Quality Control

Our production of 5-Iodo-3-(trifluoromethyl)-2-pyridinamine adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic workflows. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.