Description

5-Bromo-n-tert-Butylpyridine-3-Sulfonamide is a high-value, multi-functional sulfonamide derivative and a key synthetic intermediate in advanced organic chemistry. Its unique halogenated pyridine-sulfonamide structure makes it a versatile building block for constructing complex molecules with tailored biological and physical properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially for kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogen and sulfonamide moieties for bioactivity.
• Material Science Research: Serves as a building block for functional polymers, liquid crystals, and organic electronic materials due to its rigid aromatic core and polar sulfonamide group.
• Chemical Biology & Proteomics: Employed in the design of chemical probes and affinity tags for studying protein function and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Bromo-n-tert-Butylpyridine-3-Sulfonamide
CAS No.	911111-80-3
Molecular Formula	C9H13BrN2O2S
Molecular Weight	293.18 g/mol
Synonyms	5-Bromo-3-(tert-butylsulfamoyl)pyridine; 3-Pyridinesulfonamide, 5-bromo-N-(1,1-dimethylethyl)-; N-tert-Butyl-5-bromopyridine-3-sulfonamide; 5-Bromo-N-(tert-butyl)pyridine-3-sulfonamide; 5-Bromo-3-sulfamoyl-N-tert-butylpyridine; tert-Butyl 5-bromopyridin-3-ylsulfonylcarbamate (precursor related); 911111-80-3 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-tert-Butylpyridine-3-Sulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing parameters such as assay, identity, and impurity profiles. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.