Description

Piperaquine Tetraphosphate CAS NO 911061-10-4 is a high-purity, phosphate salt form of the potent antimalarial compound piperaquine. This form is critical for enhancing the stability and bioavailability of the active pharmaceutical ingredient in final drug formulations. It is an essential intermediate and active component for pharmaceutical manufacturers developing and producing combination therapies for malaria treatment and prophylaxis.

Application

• Active Pharmaceutical Ingredient (API) in fixed-dose combination antimalarial medications, particularly with dihydroartemisinin.
• Pharmaceutical Intermediates for the synthesis of finished dosage forms such as tablets and capsules.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.
• Research & Development of new antimalarial drugs and combination therapies in academic and institutional settings.
• Clinical Trial Material for studies evaluating the safety and efficacy of malaria treatments.
• Veterinary Pharmaceutical Applications for the treatment of parasitic infections in animals.

Basic Information

Product Name	Piperaquine Tetraphosphate
CAS No.	911061-10-4
Molecular Formula	C29H32Cl2N6 • 4H3PO4
Molecular Weight	999.56 g/mol
Synonyms	Piperaquine Phosphate; 1,3-Bis[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propane Tetraphosphate; 1,3-Bis(4-(7-chloro-4-quinolyl)-1-piperazinyl)propane Tetraphosphate; 1,3-Bis(4-(7-chloro-4-quinolyl)piperazinyl)propane Tetraphosphate; Bipiperaquine Phosphate; 13228 R.P.; RP 13228; CV 186; CV-186
EINECS	Contact for details

Quality Control

Our Piperaquine Tetraphosphate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, IR, and loss on drying, to ensure it meets high-purity pharmaceutical standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.