Description

tert-Butyl 8-[(4-Methylpiperidin-1-yl)carbonyl]-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole-2-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic indole scaffold. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in central nervous system (CNS) and oncology research. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents. The product is supplied under stringent quality control to ensure batch-to-batch consistency for critical synthetic applications.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• API Development: Employed in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs) with complex molecular architectures.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical industry.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in API production.
• Biochemical Tool Compound: Potential use in pharmacological assays to study specific biological pathways and target engagement.

Basic Information

Product Name	tert-Butyl 8-[(4-Methylpiperidin-1-yl)carbonyl]-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole-2-carboxylate
CAS No.	910797-04-5
Molecular Formula	C23H31N3O3
Molecular Weight	397.51 g/mol
Synonyms	1,3,4,5-Tetrahydro-2H-pyrido[4,3-b]indole-2-carboxylic acid, 8-[(4-methyl-1-piperidinyl)carbonyl]-, 1,1-dimethylethyl ester; tert-Butyl 8-(4-methylpiperidine-1-carbonyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-2-carboxylate; 910797-04-5; UNII-9J8F8Y0H4M; 9J8F8Y0H4M; SCHEMBL12545431; DTXSID60644688
EINECS	Contact for details

Quality Control

Our tert-Butyl 8-[(4-Methylpiperidin-1-yl)carbonyl]-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole-2-carboxylate is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for pharmaceutical research. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can support development with specifications aligned with ICH guidelines for impurities and stability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.