Description

3-(5-(Trifluoromethyl)Pyridin-2-Yl)Propanoic Acid is a high-value trifluoromethylpyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a pyridine ring and a trifluoromethyl group, makes it indispensable for creating compounds with enhanced biological activity and physicochemical properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic properties.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	3-(5-(Trifluoromethyl)Pyridin-2-Yl)Propanoic Acid
CAS No.	910654-27-2
Molecular Formula	C9H6F3NO2
Molecular Weight	217.14 g/mol
Synonyms	2-[3-(5-Trifluoromethyl-2-pyridinyl)propanoic acid]; 3-[5-(Trifluoromethyl)-2-pyridinyl]propanoic Acid; 5-(Trifluoromethyl)-2-pyridinepropionic Acid; 3-(5-Trifluoromethylpyridin-2-yl)propionic Acid; β-(5-Trifluoromethyl-2-pyridyl)propionic Acid; 910654-27-2; 3-(5-(Trifluoromethyl)pyridin-2-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our 3-(5-(Trifluoromethyl)Pyridin-2-Yl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.