Description

6-Bromo-Pyridine-2-Carboxylic Acid tert-Butyl Ester is a high-purity, versatile brominated pyridine derivative serving as a critical synthetic intermediate. Its value lies in the strategic positioning of the bromine atom and the protected carboxylic acid group, enabling efficient, multi-step organic synthesis. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for constructing complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate functionalized pyridine cores.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and R&D Laboratories: Used in medicinal chemistry and organic synthesis research for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	6-Bromo-Pyridine-2-Carboxylic Acid tert-Butyl Ester
CAS No.	910044-07-4
Molecular Formula	C10H12BrNO2
Molecular Weight	258.11 g/mol
Synonyms	tert-Butyl 6-bromopicolinate; 6-Bromopicolinic Acid tert-Butyl Ester; 2-Bromo-6-(tert-butoxycarbonyl)pyridine; 6-Bromo-2-pyridinecarboxylic Acid 1,1-Dimethylethyl Ester; 6-Bromopyridine-2-carboxylic Acid t-Butyl Ester; t-Butyl 6-bromopyridine-2-carboxylate; 910044-07-4
EINECS	Contact for details

Quality Control

Our 6-Bromo-Pyridine-2-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.