Description

7-Bromo-4-Methyl-3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure containing bromine and nitrogen. This compound is of significant commercial value as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and oncology therapeutics. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Building Block: The bromine atom provides a handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create more complex molecules.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents and pesticides.
• Material Science Exploration: Investigated for the synthesis of organic electronic materials and ligands for catalytic systems due to its nitrogen-rich heterocyclic core.

Basic Information

Product Name	7-Bromo-4-Methyl-3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine
CAS No.	910037-14-8
Molecular Formula	C8H9BrN2O
Molecular Weight	229.08 g/mol
Synonyms	7-Bromo-4-methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine; 2H-Pyrido[3,2-b]-1,4-oxazine, 7-bromo-3,4-dihydro-4-methyl-; 4-Methyl-7-bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine; 7-Bromo-4-methyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazine
EINECS	Contact for details

Quality Control

Our 7-Bromo-4-Methyl-3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.