Description

Pentafluorophenyl 6-(Tetrahydropyran-4-Yloxy)Nicotinate is a high-value, specialized chemical intermediate designed for advanced synthesis. This compound matters for its role as a key building block in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Proteomics & Bioconjugation Reagent: Used in the modification of peptides, proteins, and other biomolecules for research and diagnostic applications.
• Cross-coupling Reactions: Serves as an activated ester in palladium-catalyzed cross-coupling reactions for carbon-carbon bond formation.
• Material Science Research: Employed in the development of advanced polymers and functional organic materials with specific electronic or structural properties.
• Agrochemical Synthesis: Acts as an intermediate in the research and development of new crop protection agents and herbicides.
• Labeling and Tagging: Facilitates the introduction of fluorinated aromatic groups into molecules for tracking or to alter physicochemical properties.

Basic Information

Product Name	Pentafluorophenyl 6-(Tetrahydropyran-4-Yloxy)Nicotinate
CAS No.	910036-96-3
Molecular Formula	C18H13F5NO4
Molecular Weight	402.30 g/mol
Synonyms	6-((Tetrahydropyran-4-yl)oxy)nicotinic acid pentafluorophenyl ester; Pentafluorophenyl 6-((tetrahydro-2H-pyran-4-yl)oxy)pyridine-3-carboxylate; 6-(Oxan-4-yloxy)pyridine-3-carboxylic acid 2,3,4,5,6-pentafluorophenyl ester; PFP-6-THPO-Nicotinate; Pentafluorophenyl 6-(THPO)nicotinate; 910036-96-3; PFP active ester of 6-(tetrahydropyran-4-yloxy)nicotinic acid
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl 6-(Tetrahydropyran-4-Yloxy)Nicotinate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.