Description

Pentafluorophenyl 4-[5-(Trifluoromethyl)Pyridin-2-Yl]Benzoate is a high-value, multi-fluorinated aromatic building block designed for advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique fluorinated structure imparts desirable properties like metabolic stability and lipophilicity. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical and agrochemical industries for creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science: Serves as a precursor for synthesizing advanced polymers, liquid crystals, and organic electronic materials that require specific fluorinated aromatic components.
• Chemical Biology & Proteomics: Can be utilized as a reactive ester in bioconjugation chemistry for labeling proteins or modifying biomolecules due to the high reactivity of the pentafluorophenyl ester group.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki-Miyaura, Stille, or other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems common in medicinal chemistry.
• Synthesis of Fluorinated Liquid Crystals: Employed in the production of fluorinated mesogens for display technologies, where fluorine improves dielectric anisotropy and viscosity properties.

Basic Information

Item	Detail
Product Name	Pentafluorophenyl 4-[5-(Trifluoromethyl)Pyridin-2-Yl]Benzoate
CAS No.	910036-89-4
Molecular Formula	C19H7F8NO2
Molecular Weight	445.25 g/mol
Synonyms	4-[5-(Trifluoromethyl)-2-pyridinyl]benzoic acid pentafluorophenyl ester; 2,3,4,5,6-Pentafluorophenyl 4-[5-(trifluoromethyl)pyridin-2-yl]benzoate; Pentafluorophenyl 4-(5-(trifluoromethyl)pyridin-2-yl)benzoate; 4-(5-Trifluoromethyl-2-pyridyl)benzoic acid pentafluorophenyl ester; PFP 4-(5-TFM-pyridin-2-yl)benzoate; Pentafluorophenyl 4-(5-trifluoromethyl-2-pyridinyl)benzoate; CAS 910036-89-4
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl 4-[5-(Trifluoromethyl)Pyridin-2-Yl]Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.