Description

1-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)-1,3-Dihydro-2H-Benzimidazol-2-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. Its value lies in its role as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. This compound is essential for research and development organizations, as well as production facilities, operating in the pharmaceutical and life sciences sectors. The CAS number for this product is 909681-60-3.

Application

This specialized intermediate is designed for high-value synthesis and research applications.

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its benzimidazole and piperidine motifs.
• API Development: Serves as a critical building block in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Biochemical Tool Compound: Potential use in developing probes for studying specific biological pathways and enzyme interactions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.

Basic Information

Product Name	1-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)-1,3-Dihydro-2H-Benzimidazol-2-One
CAS No.	909681-60-3
Molecular Formula	C19H18F3N4O
Molecular Weight	375.37 g/mol
Synonyms	1-(1-((6-(Trifluoromethyl)pyridin-3-yl)methyl)piperidin-4-yl)-1,3-dihydro-2H-benzimidazol-2-one; 1-(1-[[6-(Trifluoromethyl)-3-pyridinyl]methyl]-4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one; 909681-60-3; UNII-7V2V8J8Q0K; 7V2V8J8Q0K; 2H-Benzimidazol-2-one, 1,3-dihydro-1-(1-((6-(trifluoromethyl)-3-pyridinyl)methyl)-4-piperidinyl)-; BDBM50190057; 1-(1-{[6-(Trifluoromethyl)pyridin-3-yl]methyl}piperidin-4-yl)-1H-benzimidazol-2(3H)-one
EINECS	Contact for details

Quality Control

Our 1-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)-1,3-Dihydro-2H-Benzimidazol-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.