Description

5-(5-[1-(2-Methylbenzoyl)Piperidin-4-Yl]-1,2,4-Oxadiazol-3-Yl)-2-(Trifluoromethyl)Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug candidates, especially those targeting kinase inhibition.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs within academic and industrial R&D settings.
• Active Pharmaceutical Ingredient (API) Development: A key structural component in the development of potential therapeutics for central nervous system (CNS) and inflammatory diseases.
• Biochemical Tool Compound: Employed in vitro and in vivo as a research probe to study specific biological pathways and validate novel drug targets.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Product Name	5-(5-[1-(2-Methylbenzoyl)Piperidin-4-Yl]-1,2,4-Oxadiazol-3-Yl)-2-(Trifluoromethyl)Pyridine
CAS No.	909675-91-8
Molecular Formula	C21H19F3N4O2
Molecular Weight	416.40 g/mol
Synonyms	2-(Trifluoromethyl)-5-[5-[1-(2-methylbenzoyl)-4-piperidinyl]-1,2,4-oxadiazol-3-yl]pyridine; 5-(5-(1-(2-Methylbenzoyl)piperidin-4-yl)-1,2,4-oxadiazol-3-yl)-2-(trifluoromethyl)pyridine; 909675-91-8; UNII-8X8J1K3Q1F; 8X8J1K3Q1F; CHEMBL3186663; BDBM50389384; AKOS009158269
EINECS	Contact for details

Quality Control

Our 5-(5-[1-(2-Methylbenzoyl)Piperidin-4-Yl]-1,2,4-Oxadiazol-3-Yl)-2-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom synthesis to meet specific pharmacopeial or client specifications is available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.