Description

6-[4-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)Piperazin-1-Yl]-1H-Purine is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound matters for its role as a key building block in the synthesis of targeted therapeutics, particularly in oncology and virology research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for developing novel kinase inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel small-molecule drug candidates targeting specific protein kinases.
• Oncology Research: Used in the development of targeted cancer therapies due to its purine-based scaffold, which is common in many kinase inhibitors.
• Virology Research: Serves as a building block for compounds being investigated for antiviral activity.
• Biochemical Tool Compound: Utilized in academic and industrial research to study cellular signaling pathways and enzyme function.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.
• Preclinical Development: Supplies material for early-stage pharmacological and toxicological studies of new chemical entities.

Basic Information

Product Name	6-[4-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)Piperazin-1-Yl]-1H-Purine
CAS No.	909670-78-6
Molecular Formula	C21H24F3N7
Molecular Weight	431.46 g/mol
Synonyms	1H-Purine, 6-[4-[1-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-4-piperidinyl]-1-piperazinyl]-; 6-(4-(1-((6-(Trifluoromethyl)pyridin-3-yl)methyl)piperidin-4-yl)piperazin-1-yl)-1H-purine; CAS 909670-78-6; 6-[4-[1-[[6-(Trifluoromethyl)-3-pyridinyl]methyl]-4-piperidinyl]-1-piperazinyl]purine; Purine derivative with trifluoromethylpyridine and piperazine-piperidine moiety; Kinase inhibitor intermediate 909670-78-6
EINECS	Contact for details

Quality Control

Our 6-[4-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)Piperazin-1-Yl]-1H-Purine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under inert atmosphere or with appropriate desiccants and stored away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.