Description

1-(Pyridin-2-Ylmethyl)-4-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)Piperazine is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure with a trifluoromethyl substituent. This compound is critical for research and development in medicinal chemistry, particularly for its potential role in modulating biological targets. It is primarily sought by pharmaceutical companies and contract research organizations (CROs) engaged in the synthesis of novel active pharmaceutical ingredients (APIs) for therapeutic applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its piperazine and trifluoromethylpyridine motifs.
• Biochemical Tool Compound: Employed in vitro to study enzyme inhibition or receptor binding activities in early-stage drug discovery.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial compounds for client-specific R&D projects.
• API Development: Integral to the development pathway of potential new chemical entities (NCEs) requiring high-purity, complex intermediates.

Basic Information

Product Name	1-(Pyridin-2-Ylmethyl)-4-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)Piperazine
CAS No.	909670-63-9
Molecular Formula	C22H28F3N5
Molecular Weight	419.49 g/mol
Synonyms	1-[(Pyridin-2-yl)methyl]-4-[1-[[6-(trifluoromethyl)pyridin-3-yl]methyl]piperidin-4-yl]piperazine; 4-[1-({[6-(Trifluoromethyl)pyridin-3-yl]methyl})piperidin-4-yl]-1-(pyridin-2-ylmethyl)piperazine; 909670-63-9; UNII-9J1W6H8I0F; 9J1W6H8I0F; 1-(2-Pyridylmethyl)-4-[1-[(6-trifluoromethyl-3-pyridyl)methyl]-4-piperidyl]piperazine; 1-(Pyridin-2-ylmethyl)-4-(1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperidin-4-yl)piperazine
EINECS	Contact for details

Quality Control

Our 1-(Pyridin-2-Ylmethyl)-4-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.