Description

1-(Cyclopropylcarbonyl)-4-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)Piperazine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure featuring a trifluoromethylpyridine moiety. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within the fields of central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting specific receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery pipelines.
• API Synthesis: A key building block for constructing complex molecules intended for pre-clinical and clinical development stages.
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe for studying biological pathways and enzyme interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	1-(Cyclopropylcarbonyl)-4-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)Piperazine
CAS No.	909670-30-0
Molecular Formula	C20H25F3N4O
Molecular Weight	394.44 g/mol
Synonyms	4-[1-[[6-(Trifluoromethyl)-3-pyridinyl]methyl]-4-piperidinyl]-1-(cyclopropylcarbonyl)piperazine; 1-(Cyclopropylcarbonyl)-4-[1-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-4-piperidinyl]piperazine; UNII-6F6V8V8T2Y; 6F6V8V8T2Y; 909670-30-0; 1-(cyclopropylcarbonyl)-4-(1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperidin-4-yl)piperazine
EINECS	Contact for details

Quality Control

Our production of 1-(Cyclopropylcarbonyl)-4-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)Piperazine adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.