Description

4-(2-Chloro-4-Fluorobenzyl)-1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,4-Diazepan-5-One is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially within central nervous system (CNS) and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• API Development: Serves as a precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• CNS Drug Discovery: Its diazepanone core structure makes it relevant for research into neurological and psychiatric disorders.
• Oncology Research: Potential intermediate for developing kinase inhibitors and other targeted cancer therapies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Product Name	4-(2-Chloro-4-Fluorobenzyl)-1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,4-Diazepan-5-One
CAS No.	909668-92-4
Molecular Formula	C19H18ClF4N3O
Molecular Weight	415.81 g/mol
Synonyms	1,4-Diazepan-5-one, 4-[(2-chloro-4-fluorophenyl)methyl]-1-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-; 4-[(2-Chloro-4-fluorophenyl)methyl]-1-{[6-(trifluoromethyl)pyridin-3-yl]methyl}-1,4-diazepan-5-one; CAS 909668-92-4; 4-(2-Chloro-4-fluorobenzyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1,4-diazepan-5-one
EINECS	Contact for details

Quality Control

Our 4-(2-Chloro-4-Fluorobenzyl)-1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,4-Diazepan-5-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.