Description

1-[2-Fluoro-4-(Methylsulfonyl)Phenyl]-4-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperazine is a high-value, multi-functional heterocyclic compound featuring a piperazine core flanked by fluorinated and sulfonyl-substituted aromatic systems. This advanced intermediate is critical for research and development in modern pharmaceutical chemistry, offering a versatile scaffold for creating novel active ingredients. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential new therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug discovery programs.
• Agrochemical Research: Used as a precursor in the development of novel pesticides and herbicides, leveraging its unique fluorinated and sulfonyl motifs for bioactivity.
• Chemical Biology Probe: Employed in academic and industrial research to study enzyme inhibition and receptor-ligand interactions due to its specific structural features.
• Process Chemistry & Scale-Up: A vital intermediate for process optimization and the commercial-scale production of target molecules requiring this complex chemical architecture.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific compounds under cGMP or research-grade conditions.

Basic Information

Product Name	1-[2-Fluoro-4-(Methylsulfonyl)Phenyl]-4-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperazine
CAS No.	909666-61-1
Molecular Formula	C18H17F4N3O2S
Molecular Weight	415.41 g/mol
Synonyms	4-((6-(Trifluoromethyl)pyridin-3-yl)methyl)-1-(2-fluoro-4-(methylsulfonyl)phenyl)piperazine; 1-(2-Fluoro-4-methanesulfonylphenyl)-4-[(6-trifluoromethyl-3-pyridyl)methyl]piperazine; 909666-61-1; 1-[2-Fluoro-4-(Methylsulfonyl)Phenyl]-4-[[6-(Trifluoromethyl)-3-pyridinyl]methyl]piperazine; 4-((6-(Trifluoromethyl)pyridin-3-yl)methyl)-1-(2-fluoro-4-(methylsulfonyl)phenyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-[2-Fluoro-4-(Methylsulfonyl)Phenyl]-4-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.