Description

5-(5-[1-(5-Fluoro-2-Methylbenzyl)Piperidin-4-Yl]-1,2,4-Oxadiazol-3-Yl)-2-(Trifluoromethyl)Pyridine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a sophisticated heterocyclic scaffold for creating targeted therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drugs in areas such as oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its complex piperidine-oxadiazole-pyridine core.
• API Development: Serves as a critical precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs), particularly for kinase inhibitors or receptor modulators.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Biochemical Tool Compound: Can be utilized in biochemical assays to study enzyme inhibition or receptor binding mechanisms in early-stage drug discovery.

Basic Information

Product Name	5-(5-[1-(5-Fluoro-2-Methylbenzyl)Piperidin-4-Yl]-1,2,4-Oxadiazol-3-Yl)-2-(Trifluoromethyl)Pyridine
CAS No.	909662-32-4
Molecular Formula	C22H20F4N4O
Molecular Weight	432.42 g/mol
Synonyms	2-(Trifluoromethyl)-5-[5-[1-[(5-fluoro-2-methylphenyl)methyl]-4-piperidinyl]-1,2,4-oxadiazol-3-yl]pyridine; 5-(5-(1-((5-Fluoro-2-methylbenzyl)piperidin-4-yl)-1,2,4-oxadiazol-3-yl)-2-(trifluoromethyl)pyridine; UNII-3G4J3Q9V3P; 3G4J3Q9V3P; CHEMBL3186662; BDBM50165071; AKOS009158947; ZINC000004147754
EINECS	Contact for details

Quality Control

Our 5-(5-[1-(5-Fluoro-2-Methylbenzyl)Piperidin-4-Yl]-1,2,4-Oxadiazol-3-Yl)-2-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.