Description

5-Methyl-n-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Carbonyl)Piperidin-4-Yl)Indoline-1-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, particularly in programs targeting central nervous system (CNS) and metabolic disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for CNS-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• API Development: Serves as a precursor in the multi-step synthesis of complex active pharmaceutical ingredients.
• Biochemical Research: Potential tool compound for investigating specific biological pathways and protein interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.

Basic Information

Item	Details
Product Name	5-Methyl-n-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Carbonyl)Piperidin-4-Yl)Indoline-1-Carboxamide
CAS No.	909662-28-8
Molecular Formula	C23H23F3N4O2
Molecular Weight	444.45 g/mol
Synonyms	5-Methyl-N-(1-{[6-(trifluoromethyl)pyridin-3-yl]carbonyl}piperidin-4-yl)indoline-1-carboxamide; 5-Methyl-N-(1-(6-(trifluoromethyl)nicotinoyl)piperidin-4-yl)indoline-1-carboxamide; 909662-28-8; UNII-9W5F8C3R8K; 9W5F8C3R8K; CHEMBL3186663; AKOS025147064; BDBM50389375
EINECS	Contact for details

Quality Control

Our production of 5-Methyl-n-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Carbonyl)Piperidin-4-Yl)Indoline-1-Carboxamide adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; ensure the container is kept sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.