Description

2-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,2,3,4-Tetrahydropyrazino[1,2-A]Indole is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating a trifluoromethylpyridine moiety. This compound is of significant commercial interest for its role as a key building block in the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in innovative drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs due to its unique scaffold.
• CNS Drug Development: Employed in the research of potential therapeutics for neurological disorders, leveraging the physicochemical properties imparted by its molecular structure.
• Oncology Research: Acts as a building block for potential kinase inhibitors and other targeted cancer therapies.
• Process Development & Scale-Up: Supplied to support route scouting, optimization, and pilot-scale production for clinical trial material.
• Reference Standard: Used as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Item	Details
Product Name	2-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,2,3,4-Tetrahydropyrazino[1,2-A]Indole
CAS No.	909660-89-5
Molecular Formula	C19H16F3N3
Molecular Weight	343.35 g/mol
Synonyms	2-((6-(Trifluoromethyl)pyridin-3-yl)methyl)-1,2,3,4-tetrahydropyrazino[1,2-a]indole; 2-[(6-Trifluoromethyl-3-pyridyl)methyl]-3,4-dihydro-1H-pyrazino[1,2-a]indole; Tetrahydropyrazino[1,2-a]indole, 2-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-1,2,3,4-; 909660-89-5; UNII-6J5C1HIW6T; 6J5C1HIW6T
EINECS	Contact for details

Quality Control

Our 2-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,2,3,4-Tetrahydropyrazino[1,2-A]Indole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.