Description

4-(2-Phenylethyl)-1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,4-Diazepan-5-One is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally complex building block essential for modern drug discovery programs, particularly in central nervous system (CNS) and oncology research. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to develop next-generation therapeutics with improved efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly for neurological and psychiatric disorders.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex molecules targeting specific biological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Preclinical Development: Supplied in development quantities for formulation studies, pharmacokinetic profiling, and toxicology assessments.
• Contract Research & Manufacturing (CRO/CMO): A critical raw material for organizations providing custom synthesis and scale-up services.
• Chemical Biology Probes: Can be utilized to create tool compounds for investigating biological mechanisms and target validation.

Basic Information

Product Name	4-(2-Phenylethyl)-1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,4-Diazepan-5-One
CAS No.	909659-35-4
Molecular Formula	C20H22F3N3O
Molecular Weight	377.41 g/mol
Synonyms	1,4-Diazepan-5-one, 4-(2-phenylethyl)-1-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-; 4-(2-Phenylethyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1,4-diazepan-5-one; 909659-35-4; 1-((6-(Trifluoromethyl)pyridin-3-yl)methyl)-4-phenethyl-1,4-diazepan-5-one; 4-Phenethyl-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1,4-diazepan-5-one; 5H-1,4-Diazepin-5-one, 4-(2-phenylethyl)-1-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-; CAS 909659-35-4
EINECS	Contact for details

Quality Control

Our 4-(2-Phenylethyl)-1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,4-Diazepan-5-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC, to ensure it meets the stringent requirements for pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.