Description

6-Oxaspiro[2.5]Octane-1-Carboxylic Acid is a high-value, synthetically versatile spirocyclic building block used in advanced organic synthesis. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs) due to its unique constrained three-dimensional structure. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides and fungicides with novel modes of action, leveraging its spirocyclic scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: A potential monomer or cross-linking agent for synthesizing polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	6-Oxaspiro[2.5]Octane-1-Carboxylic Acid
CAS No.	909406-73-1
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	1-Carboxy-6-oxaspiro[2.5]octane; 6-Oxaspiro[2.5]octane-1-carboxylic acid; Oxaspirooctanecarboxylic acid; Spiro[cyclopropane-1,1'-cyclohexan]-4'-one-2'-carboxylic acid, 4'-oxa-; (1R,2S)-rel-6-Oxaspiro[2.5]octane-1-carboxylic acid (for chiral forms)
EINECS	Contact for details

Quality Control

Our 6-Oxaspiro[2.5]Octane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), chiral purity (if applicable), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.