Description

2-Chloro-3-Iodo-5-[(2S)-1-Methyl-2-Pyrrolidinyl]-Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a chiral pyrrolidine substituent. This compound matters as a critical building block in the synthesis of complex, biologically active molecules, particularly for drug discovery programs targeting the central nervous system. Pharmaceutical R&D teams and fine chemical manufacturers need this precise chiral scaffold to develop new therapeutic candidates with high stereochemical fidelity.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• Ligand Synthesis: Used in the development of specialized ligands for catalysis and receptor binding studies.
• Chemical Biology Probes: Serves as a core structure for creating molecular probes to study enzyme function and cellular pathways.
• Agrochemical Research: Potential intermediate in the development of new, targeted crop protection agents with specific modes of action.
• Academic & Contract Research: Essential for universities and CROs conducting cutting-edge research in medicinal chemistry and asymmetric synthesis.

Basic Information

Product Name	2-Chloro-3-Iodo-5-[(2S)-1-Methyl-2-Pyrrolidinyl]-Pyridine
CAS No.	909193-59-5
Molecular Formula	C10H12ClIN2
Molecular Weight	322.57 g/mol
Synonyms	(S)-2-Chloro-3-iodo-5-(1-methylpyrrolidin-2-yl)pyridine; 2-Chloro-3-iodo-5-[(2S)-1-methyl-2-pyrrolidinyl]pyridine; 5-[(2S)-1-Methyl-2-pyrrolidinyl]-2-chloro-3-iodopyridine; (S)-5-(1-Methylpyrrolidin-2-yl)-2-chloro-3-iodopyridine; 909193-59-5; 2-Chloro-3-iodo-5-((S)-1-methylpyrrolidin-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Iodo-5-[(2S)-1-Methyl-2-Pyrrolidinyl]-Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chiral purity. Products undergo rigorous analytical testing, including chiral HPLC, NMR, and mass spectrometry, to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.