Description

2-Fluoro-6-(Methylamino)Pyridin-3-Ylboronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its primary value lies in its role as a versatile building block for the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Catalyst & Ligand Development: Utilized to create novel boron-containing ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring specific fluorinated pyridine scaffolds.

Basic Information

Product Name	2-Fluoro-6-(Methylamino)Pyridin-3-Ylboronic Acid
CAS No.	909187-40-2
Molecular Formula	C7H10BFN2O2
Molecular Weight	183.98 g/mol
Synonyms	(2-Fluoro-6-(methylamino)pyridin-3-yl)boronic acid; 2-Fluoro-6-(Methylamino)-3-Pyridineboronic Acid; 3-Borono-2-fluoro-6-(methylamino)pyridine; 2-Fluoro-6-methylaminopyridine-3-boronic acid; 909187-40-2; Boronic acid, B-[2-fluoro-6-(methylamino)-3-pyridinyl]-; B-[2-Fluoro-6-(methylamino)-3-pyridinyl]boronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(Methylamino)Pyridin-3-Ylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system adheres to cGMP principles where applicable, supporting our commitment to supply reliability for critical pharmaceutical development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.