Description

4-(Trifluoromethyl)Picolinimidamide is a high-value, specialized chemical building block featuring a picolinimidamide core substituted with a trifluoromethyl group. This compound is critical for researchers and manufacturers requiring precise molecular modifications to enhance the biological activity and metabolic stability of target molecules. It serves as a key synthetic intermediate for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials, particularly for customers in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the trifluoromethyl group improves binding affinity and pharmacokinetic properties.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the picolinimidamide moiety can act as a key pharmacophore.
• Ligand Synthesis for Catalysis: Serves as a precursor for creating specialized ligands used in transition metal catalysis, enabling more efficient and selective chemical transformations.
• Material Science: Employed in the research and development of advanced organic materials, such as organic semiconductors or metal-organic frameworks (MOFs), due to its unique electronic properties.
• Chemical Biology Probe Development: Utilized as a core structure for designing molecular probes to study biological processes and identify new therapeutic targets.

Basic Information

Product Name	4-(Trifluoromethyl)Picolinimidamide
CAS No.	909185-48-4
Molecular Formula	C7H6F3N3
Molecular Weight	189.14 g/mol
Synonyms	4-(Trifluoromethyl)pyridine-2-carboximidamide; 2-Pyridinecarboximidamide, 4-(trifluoromethyl)-; 4-(Trifluoromethyl)-2-pyridinecarboximidamide; 4-Trifluoromethylpicolinimidamide; Picolinimidamide, 4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 4-(Trifluoromethyl)Picolinimidamide is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, which include critical parameters such as assay (HPLC), identity confirmation (IR, NMR), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.