Description

4-(Trifluoromethyl)Picolinimidamide Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethyl-substituted picolinimidamide structure. This compound is essential for medicinal chemistry research and development, offering a critical building block for synthesizing novel bioactive molecules. It is primarily sought after by R&D teams and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for the development of new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and the creation of compound libraries for high-throughput screening.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the trifluoromethyl group.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalytic systems and metal-organic frameworks (MOFs).
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Bioconjugation and Probe Synthesis: Useful for creating chemical probes and bioconjugates for biochemical and diagnostic applications.

Basic Information

Product Name	4-(Trifluoromethyl)Picolinimidamide Hydrochloride
CAS No.	909109-68-8
Molecular Formula	C7H7ClF3N3
Molecular Weight	225.60 g/mol
Synonyms	4-(Trifluoromethyl)-2-pyridinecarboximidamide hydrochloride; 2-Pyridinecarboximidamide, 4-(trifluoromethyl)-, hydrochloride (1:1); 4-(Trifluoromethyl)picolinamidine hydrochloride; Picolinimidamide, 4-(trifluoromethyl)-, hydrochloride; 909109-68-8; 4-Trifluoromethyl-2-pyridinecarboximidamide HCl
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Picolinimidamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.