Description

2-Chloro-3-Iodopyridin-4-Amine is a halogenated pyridine derivative serving as a versatile and high-value building block in advanced organic synthesis. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive pyridine core.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Useful for creating molecular probes to study biological pathways and enzyme functions.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.
• Functional Material Development: A building block for organic electronic materials and liquid crystals.

Basic Information

Product Name	2-Chloro-3-Iodopyridin-4-Amine
CAS No.	909036-46-0
Molecular Formula	C5H4ClIN2
Molecular Weight	254.45 g/mol
Synonyms	4-Amino-2-chloro-3-iodopyridine; 2-Chloro-3-iodo-4-pyridinamine; 3-Iodo-2-chloropyridin-4-amine; 4-Pyridinamine, 2-chloro-3-iodo-; 2-Chloro-3-iodo-4-aminopyridine; 2-Chloro-3-iodo-4-pyridylamine; 909036-46-0; 2-Chloro-3-iodo-4-aminopyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Iodopyridin-4-Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.