Description

(2E)-1-(5-Bromo-2-Hydroxyphenyl)-3-(4-Chlorophenyl)Prop-2-En-1-One is a high-purity, synthetic chalcone derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for the development of novel pharmaceutical intermediates and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new active molecules with targeted properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting inflammatory pathways or possessing antimicrobial activity.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its chalcone scaffold for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a potential electron-transporting or emissive layer material in the research of organic electronic devices due to its conjugated system.
• Chemical Biology Probe: Utilized as a scaffold for creating molecular probes to study enzyme inhibition and protein-ligand interactions.
• Material Science Research: Investigated for use in nonlinear optical (NLO) materials and as a monomer for specialty polymers.
• Academic & Institutional R&D: Employed in universities and research institutes for fundamental studies in organic chemistry and medicinal chemistry.

Basic Information

Item	Detail
Product Name	(2E)-1-(5-Bromo-2-Hydroxyphenyl)-3-(4-Chlorophenyl)Prop-2-En-1-One
CAS No.	908563-74-6
Molecular Formula	C15H10BrClO2
Molecular Weight	337.60 g/mol
Synonyms	(E)-1-(5-Bromo-2-hydroxyphenyl)-3-(4-chlorophenyl)prop-2-en-1-one; 2-Propen-1-one, 1-(5-bromo-2-hydroxyphenyl)-3-(4-chlorophenyl)-, (2E)-; 5-Bromo-2-hydroxy-4'-chlorochalcone; 4'-Chloro-5-bromo-2'-hydroxychalcone; (E)-5-Bromo-2'-hydroxy-4-chlorochalcone; Chalcone derivative 908563-74-6; BR-4CL-HC
EINECS	Contact for details

Quality Control

Our (2E)-1-(5-Bromo-2-Hydroxyphenyl)-3-(4-Chlorophenyl)Prop-2-En-1-One is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available upon request, supporting compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.