Description

(E)-1-(5-Bromo-2-Hydroxy-Phenyl)-3-Phenyl-Prop-2-En-1-One is a specialized chalcone derivative, a key chemical scaffold in organic synthesis and pharmaceutical research. This compound matters for its role as a versatile synthetic intermediate, enabling the development of novel molecules with potential biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and microbial infections.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its chalcone core for bioactive molecule design.
• Organic Synthesis: Acts as a key precursor for heterocyclic compounds like flavones, pyrazolines, and other fused-ring systems via cyclization reactions.
• Material Science: Investigated as a monomer or precursor for organic semiconductors and non-linear optical (NLO) materials due to its conjugated system.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition and protein-ligand interactions.
• Flavor & Fragrance Intermediate: Potential use in the synthesis of complex aromatic compounds for specialty chemical applications.

Basic Information

Product Name	(E)-1-(5-Bromo-2-Hydroxy-Phenyl)-3-Phenyl-Prop-2-En-1-One
CAS No.	1218-22-0
Molecular Formula	C15H11BrO2
Molecular Weight	303.15 g/mol
Synonyms	5'-Bromo-2'-hydroxychalcone; (E)-5-Bromo-2-hydroxychalcone; 1-(5-Bromo-2-hydroxyphenyl)-3-phenyl-2-propen-1-one; 3-Phenyl-1-(5-bromo-2-hydroxyphenyl)-2-propen-1-one; 2-Propen-1-one, 1-(5-bromo-2-hydroxyphenyl)-3-phenyl-, (E)-; NSC 403697; Chalcone, 5'-bromo-2'-hydroxy-
EINECS	Contact for details

Quality Control

Our (E)-1-(5-Bromo-2-Hydroxy-Phenyl)-3-Phenyl-Prop-2-En-1-One is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.