Description

4-Fluorochalcone is a high-purity fluorinated chalcone derivative, a key organic building block prized for its unique photophysical and biological properties. This compound is essential for advanced research and development in medicinal chemistry and material science. It serves as a critical intermediate for pharmaceutical researchers, agrochemical developers, and organic chemists working on novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: A versatile scaffold for synthesizing novel drug candidates, particularly in anti-inflammatory, anticancer, and antimicrobial research programs.
• Agrochemical Research: Used in the development of new fluorinated pesticides and herbicides, leveraging the fluorine atom's ability to modulate bioactivity and stability.
• Organic Synthesis Building Block: A key precursor for synthesizing more complex fluorinated heterocycles and fine chemicals via reactions like cyclization and Michael addition.
• Material Science Research: Investigated for its potential in creating organic light-emitting diodes (OLEDs) and nonlinear optical (NLO) materials due to its conjugated system.
• Biochemical Probe: Utilized in biochemical studies to investigate enzyme inhibition and cellular signaling pathways.
• Academic & Industrial R&D: Serves as a standard or starting material in university laboratories and corporate R&D centers for method development and discovery chemistry.

Basic Information

Product Name	4-Fluorochalcone
CAS No.	1608-51-1
Molecular Formula	C15H11FO
Molecular Weight	226.25 g/mol
Synonyms	(E)-1-(4-Fluorophenyl)-3-phenylprop-2-en-1-one; 4'-Fluorochalcone; 3-Phenyl-1-(4-fluorophenyl)-2-propen-1-one; 1-(4-Fluorophenyl)-3-phenyl-2-propen-1-one; 4-Fluorobenzalacetophenone; p-Fluorochalcone; F-Chalcone
EINECS	Contact for details

Quality Control

Our 4-Fluorochalcone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	88 - 92 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.