Description

4Nitrochalcone (CAS NO 1152-48-3) is a synthetic organic compound belonging to the chalcone family, characterized by a nitro-substituted aromatic ketone structure. This compound serves as a versatile chemical intermediate and a valuable scaffold in pharmaceutical and materials research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel bioactive molecules and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those targeting inflammation, cancer, and microbial infections.
• Organic Synthesis Research: Acts as a precursor for heterocyclic compounds like pyrazolines and flavones through various cyclization and condensation reactions.
• Agrochemical Development: Used in research to create novel pesticides and herbicides by exploiting its bioactive chalcone core.
• Material Science: Investigated as a component in the development of organic semiconductors, non-linear optical (NLO) materials, and photoactive polymers.
• Biochemical Probe: Serves as a tool compound in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Academic & Industrial R&D: Essential for method development, library synthesis, and discovery chemistry in both university and corporate laboratory settings.

Basic Information

Product Name	4Nitrochalcone
CAS No.	1152-48-3
Molecular Formula	C15H11NO3
Molecular Weight	253.25 g/mol
Synonyms	(E)-3-(4-Nitrophenyl)-1-phenylprop-2-en-1-one; 4'-Nitrochalcone; 3-(4-Nitrophenyl)-1-phenyl-2-propen-1-one; 1-Phenyl-3-(4-nitrophenyl)-2-propen-1-one; Chalcone, 4'-nitro-; 4-Nitrobenzalacetophenone; NSC 406913; p-Nitrochalcone
EINECS	214-557-6

Quality Control

Our 4Nitrochalcone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and loss on drying. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Standard Grade)
Melting Point	158°C - 162°C
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.