Description

(E)-1-(5-Chloro-2-Hydroxyphenyl)-3-Phenylprop-2-En-1-One is a high-purity, synthetic chalcone derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical pharmaceutical intermediate and research chemical for developing novel bioactive molecules. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates with potential anti-inflammatory, anticancer, or antimicrobial properties.
• Organic Synthesis Reagent: Used in research laboratories for Michael additions, cyclization reactions, and the construction of complex heterocyclic compounds.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides due to its bioactive chalcone scaffold.
• Material Science: Investigated as a monomer or precursor for functional organic materials and polymers.
• Biochemical Research: Utilized in studies exploring enzyme inhibition and other biological pathways.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(E)-1-(5-Chloro-2-Hydroxyphenyl)-3-Phenylprop-2-En-1-One
CAS No.	1218-24-2
Molecular Formula	C15H11ClO2
Molecular Weight	258.70 g/mol
Synonyms	5'-Chloro-2'-hydroxychalcone; (E)-1-(5-Chloro-2-hydroxyphenyl)-3-phenyl-2-propen-1-one; 3-(5-Chloro-2-hydroxyphenyl)-1-phenyl-2-propen-1-one; 2-Propen-1-one, 1-(5-chloro-2-hydroxyphenyl)-3-phenyl-, (E)-; Chalcone, 5'-chloro-2'-hydroxy-; NSC 403697
EINECS	Contact for details

Quality Control

Our (E)-1-(5-Chloro-2-Hydroxyphenyl)-3-Phenylprop-2-En-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.