Description

4',6'-Dimethoxy-2'-Hydroxychalcone is a specialized chalcone derivative, a key intermediate in organic synthesis and pharmaceutical research. This compound matters for its role as a versatile building block in the development of novel bioactive molecules, particularly in medicinal chemistry. It is needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on creating new therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and metabolic disorders.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Natural Product Synthesis: Used in the laboratory synthesis and structural modification of naturally occurring flavonoids and related polyphenolic compounds.
• Biochemical Probe Development: Employed in the creation of molecular probes to study enzyme interactions and cellular signaling pathways.
• Fine Chemical Manufacturing: Acts as a key building block for producing high-value, complex organic molecules for various industrial applications.
• Academic Research: Utilized in universities and research institutes for studies in organic synthesis methodologies and heterocyclic chemistry.

Basic Information

Product Name	4',6'-Dimethoxy-2'-Hydroxychalcone
CAS No.	1775-97-9
Molecular Formula	C₁₉H₂₀O₅
Molecular Weight	328.36 g/mol
Synonyms	2'-Hydroxy-4',6'-dimethoxychalcone; (E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one; 4,6-Dimethoxy-2-hydroxychalcone; NSC 407347; Chalcone, 2'-hydroxy-4',6'-dimethoxy-; 1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-phenyl-2-propen-1-one
EINECS	Contact for details

Quality Control

Our 4',6'-Dimethoxy-2'-Hydroxychalcone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep the container tightly sealed when not in use to minimize exposure to air.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.