Description

7-Chlorothiazolo[4,5-C]Pyridine-2-Thiol is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its role as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex nitrogen- and sulfur-containing heterocycles. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Research: Used in the development of new herbicides and fungicides that leverage its unique thiazolopyridine scaffold.
• Material Science Precursor: Serves as a precursor for ligands and functional molecules in catalysis and advanced material applications.
• Chemical Biology Probe: Utilized in the design of molecular probes and biochemical tools for studying enzyme function and cellular pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	7-Chlorothiazolo[4,5-C]Pyridine-2-Thiol
CAS No.	908355-84-0
Molecular Formula	C6H2ClN2S2
Molecular Weight	216.68 g/mol
Synonyms	7-Chloro-2-mercaptothiazolo[4,5-c]pyridine; 2-Thiol-7-chlorothiazolo[4,5-c]pyridine; 7-Chloro-2-thioxo-2,3-dihydrothiazolo[4,5-c]pyridine; 7-Chloro-2,3-dihydrothiazolo[4,5-c]pyridine-2-thione; 908355-84-0; Thiazolo[4,5-c]pyridine-2-thiol, 7-chloro-; 7-Chloro-2-sulfanyl-[1,3]thiazolo[4,5-c]pyridine
EINECS	Contact for details

Quality Control

Our 7-Chlorothiazolo[4,5-C]Pyridine-2-Thiol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.