Description

(R)-5,11-Dimethyl-2,8-Bis(Trifluoromethyl)-1,7-Dioxaspiro[5.5]Undeca-2,4,8,10-Tetraene is a high-purity, chiral spirocyclic compound distinguished by its unique molecular architecture and the presence of trifluoromethyl groups. This compound serves as a versatile and advanced intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research where its stereochemistry and fluorine content are critical for activity. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Chiral Catalyst/Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in asymmetric catalysis.
• Material Science: Potential monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Fluorine Chemistry Studies: A valuable reference compound for investigating structure-activity relationships (SAR) influenced by fluorine atoms.
• Academic & Institutional Research: Employed in universities and research institutes for methodological development in organic synthesis.

Basic Information

Product Name	(R)-5,11-Dimethyl-2,8-Bis(Trifluoromethyl)-1,7-Dioxaspiro[5.5]Undeca-2,4,8,10-Tetraene
CAS No.	908338-80-7
Molecular Formula	C15H12F6O2
Molecular Weight	338.25 g/mol
Synonyms	(R)-5,11-Dimethyl-2,8-bis(trifluoromethyl)-1,7-dioxaspiro[5.5]undeca-2,4,8,10-tetraene; (R)-Spirobis(4-methyl-6-(trifluoromethyl)-2H-1,3-dioxine); (R)-2,2',5,5'-Tetramethyl-4,4'-bis(trifluoromethyl)-2,2'-bi(1,3-dioxine); (R)-DMDTFDOSU; (R)-enantiomer of Dioxaspiro Compound 908338-80-7; Light-sensitive (store away from light) compound.
EINECS	Contact for details

Quality Control

Our (R)-5,11-Dimethyl-2,8-Bis(Trifluoromethyl)-1,7-Dioxaspiro[5.5]Undeca-2,4,8,10-Tetraene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure compliance with client specifications and research-grade standards. Comprehensive Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.