Description

1-Azetidinecarboxylic Acid, 3-(2-Carboxyphenyl)-, 1-(1,1-Dimethylethyl) Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting complex disease pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, including protease inhibitors and other specialized small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry research.
• Protease Inhibitor Development: Serves as a core scaffold for designing and synthesizing potential inhibitors for various protease enzymes.
• Chemical Biology Research: Used as a specialized reagent in studying enzyme-substrate interactions and signal transduction pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for clinical trials.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	1-Azetidinecarboxylic Acid, 3-(2-Carboxyphenyl)-, 1-(1,1-Dimethylethyl) Ester
CAS No.	908334-12-3
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	tert-Butyl 3-(2-carboxyphenyl)azetidine-1-carboxylate; 3-(2-Carboxyphenyl)azetidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-(2-carboxyphenyl)azetidine; 3-(2-Carboxy-phenyl)-azetidine-1-carboxylic acid tert-butyl ester; BOC-3-(2-COOH-Phenyl)azetidine; Azetidine-1-carboxylic acid, 3-(2-carboxyphenyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of 1-Azetidinecarboxylic Acid, 3-(2-Carboxyphenyl)-, 1-(1,1-Dimethylethyl) Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity suitable for research and pharmaceutical applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.