Description

2-Chloro-4-Cyano-3-Iodopyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring chloro, cyano, and iodo substituents, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its reactive halogen sites.
• Material Science: Serves as a building block for creating functionalized ligands, organic semiconductors, and liquid crystal compounds.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Stille couplings.
• Nucleophilic Substitution: The chloro and cyano groups provide sites for further functionalization with various nucleophiles.
• Chemical Biology: Utilized as a probe or tag in bioconjugation chemistry and for modifying biomolecules.

Basic Information

Product Name	2-Chloro-4-Cyano-3-Iodopyridine
CAS No.	908279-56-1
Molecular Formula	C6H2ClIN2
Molecular Weight	263.45 g/mol
Synonyms	3-Iodo-2-chloro-4-cyanopyridine; 2-Chloro-3-iodo-4-pyridinecarbonitrile; 4-Cyano-2-chloro-3-iodopyridine; 908279-56-1; Pyridine, 2-chloro-4-cyano-3-iodo-; 2-Chloro-3-iodopyridine-4-carbonitrile; 3-Iodo-2-chloropyridine-4-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Cyano-3-Iodopyridine is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.